Diagnosis of Marek’s Disease in Isa Brown Layer Chicken based on Anatomical Pathology and Histopathological Examination

Abstract Marek’s disease and reticuloendotheliosis are neoplastic diseases in poultry infected by virus (MDV) (REV), respectively. This infection may lead to tumor growth the chicken organ which is difficult distinguish based on macroscopic lesions, therefore it important further diagnose histopathological examination. Thus, this study aimed layer anatomical pathology histopathology The samples used were ten cadavers of culled Isa Brown that died market. immediately transported Pathology Laboratory for necropsy macroscopically tumors observed pancreas mesenteric organs collected then proceeded examination followed staining using hematoxylin-eosin (HE) Masson’s trichrome (MT). showed numerous white-colorized vary size found mesenteries pancreas. Histopathological demonstrated consisted inflammatory cells reticular cells. pleomorphic basophilic lymphocytes. In conclusion, study, diagnosis visceral type ISA brown means was characterized nodules organs. While microscopically tissue consists connective lymphocytes with large cell sizes, varying shapes, colors.